The Course of Apparent Diffusion Coefficient Values following Perinatal Arterial Ischemic Stroke

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The Course of Apparent Diffusion Coefficient Values following Perinatal Arterial Ischemic Stroke

BACKGROUND Diffusion weighted MR imaging (DWI) plays an important role in the diagnosis of perinatal arterial ischemic stroke (PAIS) during the acute phase. Its derived apparent diffusion coefficient (ADC) can be used to quantify the diffusion restriction. Aim of the current study was to identify the changes in ADC values in the acute phase following PAIS. METHODS A cohort of 36 infants with ...

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Diffusion-weighted MRI (DWI) is a sensitive and reliable marker of cerebral ischemia. Within minutes of an ischemic event in the brain, the microscopic motion of water molecules measured with DWI, termed the apparent diffusion coefficient (ADC), decreases within the infarcted region. However, although the change is related to cell swelling, the precise pathological mechanism remains elusive. We...

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Figure 2. (a) ADC (unit 1×10 mm/s) changes in the presence and absence of reperfusion; (b)histogram of tp2 ADC in the reperfused ROI that did (infarct) and did not (noninfarct) go on infarction. The two vertical lines show ADC abnormal threshold (left) and normal mean (right). Figure 1. Representative ADC, MTT at tp1 and tp2 and FLAIR at tp3 from two patients. The range of the colorbar is from ...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2013

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0056784